Motor unit firing pattern of vastus lateralis muscle in type 2 diabetes mellitus patients /

Introduction We investigated the motor unit (MU) firing pattern in type 2 diabetes mellitus (T2DM) patients by means of multi-channel surface electromyography (SEMG). Methods Eight T2DM patients and 8 age-matched healthymen performed a ramp-up contraction up to 20% of maximal voluntary contraction (...

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Main Authors: Watanabe, Kohei. (Author), Gazzoni, Marco. (Author), Holobar, Aleš. (Author), Miyamoto, Toshiaki. (Author), Fukuda, Kazuhito. (Author), Merletti, Roberto. (Author), Moritani, Toshio. (Author)
Format: Book Chapter
Jezik:English
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Sorodne knjige/članki:Vsebovano v: Muscle & nerve
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024 7 1 |a 10.1002/mus.23828  |2 doi 
040 |a KTFMB  |b slv  |c SI-MaIIZ  |d KTFMB  |e ppiak 
041 0 |a eng  |b eng 
080 |a 61  |2 UDCMRF 2006 
245 1 0 |a Motor unit firing pattern of vastus lateralis muscle in type 2 diabetes mellitus patients /   |c Kohei Watanable ... [et al.].  
300 |a str. 806-813. 
500 |a Soavtorji: Marco Gazzoni, Ales Holobar, Toshiaki Miyamato, Kazuhito Fukuda, Roberto Merletti, Toshio Moritani.  
504 |a Bibliografija: str. 813.  
504 |a Abstract.  
520 |a Introduction We investigated the motor unit (MU) firing pattern in type 2 diabetes mellitus (T2DM) patients by means of multi-channel surface electromyography (SEMG). Methods Eight T2DM patients and 8 age-matched healthymen performed a ramp-up contraction up to 20% of maximal voluntary contraction (MVC). They also performed a sustained contraction at 10% of MVC during isometric knee extension. Multi-channel SEMG signals recorded from the vastus lateralis muscle were decomposed with the Convolution Kernel Compensation technique to extract individual MU firing patterns. Results During the ramp contraction, the extent of MU firing modulation was significantly attenuated in T2DM. Variability of MU firing rate was significantly higher in T2DM at later periods during the sustained contraction. Discussion Our findings suggest that T2DM patients manifest characteristic MU activity patterns due possibly to some degree of neuromuscular impairment affecting the integrity of MU firing modulation.  
653 0 |a type 2 diabetes mellitus  |a multichannel surface electromyography  |a knee extensors  |a vastus lateralis  |a firing rate 
700 1 |a Watanabe, Kohei.   |4 aut 
700 1 |a Gazzoni, Marco.   |4 aut 
700 1 |a Holobar, Aleš.   |4 aut 
700 1 |a Miyamoto, Toshiaki.   |4 aut 
700 1 |a Fukuda, Kazuhito.   |4 aut 
700 1 |a Merletti, Roberto.   |4 aut 
700 1 |a Moritani, Toshio.   |4 aut 
773 0 |t Muscle & nerve  |b [Online ed.]  |d New York, NY : John Wiley & Sons, 1978-  |x 1097-4598  |g Vol. 48 (Nov. 2013), str. 806-813