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Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma

Malignant melanoma is a highly aggressive form of skin cancer responsible for the majority of skin cancer-related deaths. Recent insight into the heterogeneous nature of melanoma suggests more personalised treatments may be necessary to overcome drug resistance and improve patient care. To this end,...

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Main Authors: Rožanc, Jan, biolog. (Author), Sakellaropoulos, Theodore. (Author), Antoranz, Asier. (Author), Guttà, Cristiano. (Author), Podder, Biswajit. (Author), Vetma, Vesna. (Author), Rufo, Nicole. (Author), Agostinis, Patrizia. (Author), Pliaka, Vaia. (Author), Sauter, Thomas. (Author), Kulms, Dagmar. (Author), Rehm, Markus. (Author), Alexopoulos, Leonidas G. (Author)
Format: Book Chapter
Jezik:English
Teme:
Melanoma > Drug Resistance > Treatment Outcome.
Skin Neoplasms > Cell Line.
Melanom > odpornost na zdravila > izid zdravljenja.
Kožne novotvorbe > celična linija.
Online dostop:https://www.nature.com/articles/s41418-018-0210-8
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https://www.nature.com/articles/s41418-018-0210-8

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