Construction of new immunotoxins by linking equinatoxin II to monoclonal antibodies via the biotin-avidin interaction. Cytotoxic effects on human tumor cells = Citotoksični efekti imunotoxinov sestavljenih iz ekvinatoksina II in monoklonskih protiteles na človeške tumorske celice /
The pore-forming protein equinatoxin II (EqtII) from Actinia equina, and five single cysteine EqtII mutants (K20C, K77C, R126C, R144C, A179C), were evaluated for the preparation of specific immunotoxins (IT). They were linked to a monoclonal antibody (mAb) specific for tumor cells via the high affin...
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Main Authors: | Potrich, Cristina. (Author), Anderluh, Gregor, 1969- (Author), Maček, Peter. (Author) |
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Format: | Book Chapter |
Jezik: | English |
Teme: | |
Sorodne knjige/članki: | Vsebovano v:
Acta biologica slovenica |
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